An Exploratory, Randomized, Double-Blind Clinical Trial of Dipraglurant for Blepharospasm
Published in Movement Disorders, 2024
Recommended citation: Kilic-Berkmen G, Kim H, Chen D, Yeo CI, Dinasarapu AR , Scorr LM, Yeo WH, Peterson DA, Williams H, Ruby A, Mills R, Jinnah HA (2024) An Exploratory, Randomized, Double-Blind Clinical Trial of Dipraglurant for Blepharospasm. Movement Disorders (2024) https://doi.org/10.1002/mds.29734
This study was an exploratory, phase 2a, randomized, double-blind, placebo-controlled trial of 15 participants who were assigned to receive a placebo or dipraglurant (50 or 100 mg) and assessed over 2 days, 1 and 2 hours following dosing. Outcome measures included multiple scales rated by clinicians or participants, digital video, and a wearable sensor.