Comprehensive measurement of purines in biological samples.
Published in Frontiers in Analytical Science, 2025
Recommended citation: Fu R, Sutcliffe DJ, Dinasarapu AR , Hess EJ and Jinnah HA (2025) Comprehensive measurement of purines in biological samples. Front. Anal. Sci. 5:1600781. https://doi.org/10.3389/frans.2025.1600781
Defects in numerous aspects of purine metabolism are well-recognized causes for human diseases. The applicability of ultra performance liquid chromatography (UPLC) with photodiode array (PDA) detection for analysis of the most abundant biological relevant purines metabolites is described.